野生红叶副产品的增值:提取,生物活性化合物,抗氧化活性和纳米配方
Valentina Masala1, Simona Demuro1, Gabriele Serreli2
1Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, S.P. Monserrato-Sestu km 0.700, 09042 Monserrato, Italy.
Food chemistry
|February 25, 2026
概括
野生叶提取物,富含化合物,被封装在聚合物涂层的脂质体中. 这种纳米配方表现出显著的抗氧化特性和稳定性,表明其对功能性食品的潜力.
科学领域:
- 植物化学 植物化学
- 食品科学 食品科学 食品科学
- 纳米技术纳米技术
背景情况:
- 野生红 (Cynara cardunculus亚种) 是一种植物. cardunculus L.) 是一种地中海植物,具有已知的营养和健康益处.
- 叶子副产品是有价值的生物活性化合物的潜在来源.
研究的目的:
- 为了表征野生红叶提取物中的化合物.
- 开发和评估提取物用于口服的纳米配方.
- 评估纳米配方提取物的抗氧化潜力和稳定性.
主要方法:
- 使用不同的乙醇-水混合物提取野生叶.
- 用LC-ESI-QTOFMS/MS和HPLC-PDA对化合物的定量分析.
- 将提取物封装成纳米尺寸的肠道聚合物涂层脂质体.
- 在体外抗氧化剂测定 (无细胞和基于细胞的模型).
- 在模拟和ex vivo胃肠道条件下进行稳定性研究.
主要成果:
- 基酸和黄被确定为主要的化合物.
- 以80:20%的EtOH:H2O (WCE2) 获得的提取物显示了最高的含量.
- 纳米化肠道聚合物涂层脂质体实现了WCE2.2的高捕获效率.
- 该纳米配方在储存和模拟消化过程中表现出显著的抗氧化活性和良好的稳定性.
结论:
- 野生红叶提取物是抗氧化剂的丰富来源,主要是基酸和黄酸.
- 聚合物涂层脂质体提供了一个有效的纳米输送系统,用于口服提取物.
- 纳米配方的野生卡尔多提取物由于其抗氧化特性和稳定性,有望发展成为功能性食品.
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