EAT-Lancet饮食模式的坚持和与代谢功能障碍相关的脂肪性肝病:阿莫尔队列研究的横截面分析
Azam Doustmohammadian1, Saeed Esfandyari1, Nima Motamed2
1Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
The Journal of nutrition
|February 25, 2026
概括
坚持EAT-Lancet行星健康饮食可能会降低与代谢功能障碍相关的脂肪性肝病 (MASLD) 的风险. 在伊朗的一项人口研究中,这种保护作用特别在女性身上被发现.
科学领域:
- 营养科学 营养科学
- 肝病学 肝病学是一种肝病学.
- 流行病学 流行病学
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 是一个日益严重的全球健康挑战.
- 建议使用EAT-Lancet行星健康饮食来缓解MASLD,但对中东人口的证据很少.
研究的目的:
- 调查遵守EAT-Lancet饮食与伊朗队列中MASLD流行率之间的关联.
- 探索剂量反应关系和性别特异性影响.
主要方法:
- 在伊朗北部的Amol队列研究 (AmolCS) 中,对2937名参与者的横截面研究.
- 通过168项食物频率问卷来评估饮食摄入量,以计算EAT-Lancet的坚持.
- 使用腹部超声波诊断的MASLD;用于分析的多变量逻辑回归.
主要成果:
- 40%的参与者患有MASLD,表现出较差的代谢概况.
- 较高的EAT-Lancet饮食坚持与较低的MASLD (OR 0.62;95%CI 0.48-0.82) 患病率有关.
- 反向关联在女性中更强,鱼类,豆类,蛋和土豆显示出保护性贡献.
结论:
- 增加对EAT-Lancet饮食的坚持与伊朗人口中减少MASLD患病率相关.
- 研究结果表明,植物向前饮食可能有利于新陈代谢性肝脏健康,特别是在女性中.
- 需要进一步的研究,包括前性和干预性研究,以确认因果关系.
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