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Updated: Feb 28, 2026

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"自上而下的生理学基础的有限时间药理动力学 (PBFTPK) 模型为早期药物开发开辟了一条新途径

Athina Kalantzi1, Antony Simitopoulos1, Athanasios A Tsekouras2

  • 1Faculty of Pharmacy, Laboratory of Biopharmaceutics Pharmacokinetics, National and Kapodistrian University of Athens, Athens, Greece.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|February 25, 2026
PubMed
概括

基于生理学的有限时间药理动力学 (PBFTPK) 模型重新定义了早期药物开发的吸收数 (An). 这种方法提供了对药物吸收特征和运输机制的洞察,有助于预测药物行为.

关键词:
这就是F.A.T.T.有限的吸收时间.口服吸收 口服吸收药理动力学 药理动力学基于生理学的有限时间药物动力学模型 PBFTPKK

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