患者血液管理和血液制品替代品:一个更新
Hollie M Reeves1, Kathleen K Nicol1
1Transfusion Medicine Services, Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA.
Clinics in laboratory medicine
|February 25, 2026
概括
患者血液管理策略通过解决风险和优化血液使用来最大限度地减少输血. 对替代品的持续研究对于保护捐献者血液资源至关重要.
科学领域:
- 输血医学 输血医学
- 麻醉学 麻醉学
- 手术护理 手术护理
背景情况:
- 患者血液管理 (PBM) 对于尽量减少与输血相关的风险,成本和浪费至关重要.
- 捐献者血液的可用性和病原体的传播是医疗保健中的重要问题.
- 优化血液产品的利用对于资源的保护至关重要.
研究的目的:
- 审查患者血液管理当前的策略.
- 为了强调尽量减少全基血输血的重要性.
- 强调对血液替代品和资源保护的持续需求.
主要方法:
- 关于患者血液管理技术的当前文献的综述.
- 分析包括限制性输血协议在内的策略.
- 对外科手术期间贫血管理和静血剂的检查.
主要成果:
- PBM策略有效地减少了血液损失和输血需求.
- 限制性输血门和贫血管理是PBM的关键组成部分.
- 血液替代品的开发仍然是一个活跃的研究领域.
结论:
- 有效的患者血液管理对于优化血液产品使用和患者安全至关重要.
- 尽管取得了进展,但依赖献血者血液需要在PBM和替代品方面不断进行创新.
- 保护捐献者血液资源需要一个多方面的方法,结合当前的策略和未来的研究.
相关概念视频
Blood Transfusion and Agglutination
15.1K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
15.1K
Blood Transfusion
2.6K
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
2.6K
Blood Typing
3.1K
Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
3.1K
Bone Marrow Sampling and Transplants
1.8K
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
1.8K
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence
232
Generic intravenous (IV) drugs are considered bioequivalent to their branded counterparts due to their 100% bioavailability upon administration. However, variations in stability among different drug products can significantly influence their therapeutic performance, even if they are pharmaceutically equivalent.Cefuroxime, a prophylactic antimicrobial, is often used as a single-dose IV injection for patients undergoing coronary artery bypass grafting surgery. A 3 g dose typically provides...
232
The ABO Blood Group
5.5K
The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
5.5K


