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相关概念视频

Brain Imaging01:14

Brain Imaging

797
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
797

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相关实验视频

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A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion
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定位与运动相关的脑震荡,并用多模式脑成像来描述恢复轨迹.

Natalie M Bell1, James M Holcomb1, Sarah G Holmes1

  • 1From the Advanced Neuroscience Imaging Research (ANSIR) Lab, Department of Radiology (N.M.B., J.M.H., S.G.H., M.R.B., C.J., F.F.U., J.A.M., E.M.D.), Biomedical Engineering (J.M.H., F.F.U., J.A.M., E.M.D.), Psychiatry (M.C.), Neurological Surgery (M.C.), Pediatrics (A.T., M.S.) and Neurology (A.T., M.S.), University of Texas Southwestern Medical Center, Dallas, TX, USA.

AJNR. American journal of neuroradiology
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PubMed
概括

这项研究使用多式脑成像来追踪一名青少年足球运动员脑震荡恢复的情况. 研究结果显示,脑部变化如血流减少和脑部活动改变后脑震荡,突出显示成像.

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科学领域:

  • 神经科学是一个神经科学.
  • 运动医学 运动医学
  • 放射学 放射学是一门学科.

背景情况:

  • 与运动有关的脑震荡在高中运动员中很常见.
  • 了解脑震荡的神经生物学影响对于恢复和回归游戏决策至关重要.
  • 多模式神经成像提供了一种全面的方法来评估大脑功能和结构.

研究的目的:

  • 为了比较最近脑震荡和没有脑震荡的双胞胎双胞胎之间的神经生理学和神经成像发现.
  • 通过使用多模式方法,研究首次脑震荡的急性和亚急性影响.
  • 评估先进成像技术在局部化脑震荡效应和告知临床管理方面的潜力.

主要方法:

  • 使用磁脑电图 (MEG),电脑电图 (EEG),扩散曲解成像 (DKI),伪连续动脉旋转标记 (pCASL) 和静止状态功能性MRI (rs-fMRI).
  • 在三个时间点 (T1:脑震荡后72小时,T2:1个月,T3:3个月) 中比较了一个脑震荡的双胞胎 (A双胞胎) 和她没有脑震荡的双胞胎姐妹 (B双胞胎).
  • 在3T西门子Prisma扫描仪和MEGIN Triux Neo系统上使用协调协议获取数据.

主要成果:

  • 脑震荡的双胞胎 (A双胞胎) 呈现出急性症状,左额外输液,减少rs-fMRI功率,并在T1.1时增加低频电生理活动.
  • 在3个月的时间里,双胞胎A在所有评估的模式中都表现出逐渐的恢复.
  • 没有脑震荡的双胞胎 (B双胞胎) 在所有评估中显示出稳定的结果,作为有效的对照.

结论:

  • 多式脑成像可以有效地检测和定位与体育相关脑震荡相关的神经生物学变化.
  • 这些先进的成像技术在客观地告知运动员的回归决策方面表现有前途.
  • 这项研究强调了将受影响的双胞胎与未受影响的双胞胎进行比较对于理解脑震荡病理生理学的有用性.