相关实验视频

Updated: Feb 28, 2026

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications

Published on: February 23, 2019

通知一个医学科目标题 (MeSH) 请求: "处方布"案例研究

Fernando Fernandez-Llimos¹, Fernanda S Tonin²

¹Applied Molecular Biosciences Unit (UCIBIO), Institute for Health and Bioeconomy (i4HB), Laboratory of Pharmacology, Faculty of Pharmacy, University of Porto, Porto, Portugal.

Research in social & administrative pharmacy : RSAP

|February 25, 2026

概括

目前不需要专门的医学科目标题 (MeSH) 术语来表示"处方级联". 现有的MeSH术语充分捕捉了这一概念,这表明重点应该转向改进索引策略以实现更好的检索.

科学领域:

药监和药物安全药监和药物安全
医疗信息学和受控制的词汇
医疗保健服务研究医疗服务研究

背景情况:

处方级联,在这种级联中,针对被误认为新疾病的不良药物效应,开始新疗法,这对准确的医学索引构成了挑战.
目前,对于这种现象,没有特定的医学科目标题 (MeSH) 术语,这阻碍了准确的文献检索.
这项研究研究了专门的MeSH术语的必要性,用于规定级联,以及其对索引一致性的潜在影响.

研究的目的:

评估是否需要一个新的MeSH术语来表示"处方布".
评估现有的MeSH术语是否足够用于对处方级联的文献进行索引和检索.
分析潜在的新MeSH术语对索引一致性和检索准确性的影响.

主要方法:

从范围审查中对139篇文章进行了横截面分析.
使用PubMed和MEDLINE元数据来检查选定的文章的MeSH术语归因.
统计分析,包括95%置信区间 (CI) 的几率比率 (OR),关键词之间的量化关联 (例如",不合适"",不利"",级联") 和分配的MeSH术语.

主要成果:

对106篇MEDLINE索引文章的分析揭示了流行的MeSH术语,包括"与药物相关的副作用和不良反应" (32.1%),"多药" (30.2%) 和"不适当的处方" (26.4%).
关键词分析显示了显著的关联:标题中的"不合适"预测了"潜在不合适的药物清单" (OR=204),摘要中的"不良"预测了"与药物相关的副作用和不良反应" (OR=2.8).
标题中的"级联"术语与"与药物相关的副作用和不良反应" (OR=3.6) 相联系,表明一些现有的术语捕捉了处方级联的各个方面.

结论:

这些发现表明,目前的MeSH描述器足以捕捉处方级联的主要维度.
目前没有证据支持为"处方布"创建专门的MeSH术语.
未来的研究应该集中在达成定义共识和开发组成索引策略,以提高这个概念的检索准确性.

关键词:

文献资料数据库文献资料数据库控制的词汇管理管理词汇管理信息的存储和检索.术语作为一个主题.

更多相关视频

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

相关概念视频

Methods of Documentation VI: Case Management Model

Methods of Documentation VI: Case Management Model

The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...

Case Studies

Case Studies

There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.

Mesh Analysis

Mesh Analysis

Mesh analysis is a valuable method for simplifying circuit analysis using mesh currents as key circuit variables. Unlike nodal analysis, which focuses on determining unknown voltages, mesh analysis applies Kirchhoff's voltage law (KVL) to find unknown currents within a circuit. This method is particularly convenient in reducing the number of simultaneous equations that need to be solved.
A fundamental concept in mesh analysis is the definition of meshes and mesh currents. A mesh is a closed...

Clinical Trials: Overview

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...

Classification of Illness

Classification of Illness

The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...

Drug Nomenclature

Drug Nomenclature

During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that...