包容性问题:描述俄克拉荷马州美国印第安人/阿拉斯加本土人的CF健康不平等
Amy D Hendrix-Dicken1, Emily Christein2, Jillian Landers3
1Department of Pediatrics, University of Oklahoma School of Community Medicine, Tulsa, OK, USA; Citizen of the Cherokee Nation, Cherokee Reservation, USA.
概括
美国印第安人和阿拉斯加原住民 (AI/AN) 患有囊性纤维化 (CF) 的孩子的住院率更高. 这凸显了严重的健康差异,以及需要针对AI/AN人群制定有针对性的CF健康公平倡议.
科学领域:
- 呼吸系统健康 呼吸系统健康
- 健康差异 在健康上的差异
- 遗传学和基因组学 遗传学和基因组学
背景情况:
- 美国印第安人和阿拉斯加原住民 (AI/AN) 社区经历了显著的呼吸系统健康差异,包括更高的囊性纤维化 (CF) 率.
- 了解患有CF的AI/AN个体的特定健康状况和人口结构对于解决这些差异至关重要.
研究的目的:
- 描述俄克拉荷马州CF的AI/AN个体的人口特征.
- 为了比较AI/AN CF个体的健康状况与俄克拉荷马州CF的非西班牙裔白人个体.
主要方法:
- 追溯分析2023年CF基金会患者登记数据.
- 根据种族/种族和年龄分类的AI/AN和非西班牙裔CF白人的比较.
- 统计分析包括千平方,费舍尔的确切,韦尔奇的t测试,曼-惠特尼U测试 (p < .05).
主要成果:
- 与非西班牙裔白人儿童相比,患有CF的AI/AN儿童的全因住院/家庭静脉注射使用率 (31.3%对13.2%) 和肺部恶化率 (22.9%对6.6%) 显著更高.
- AI/AN儿童的阳性细菌/真菌培养率较高,并患有CF相关糖尿病等并发症.
- 成年AI/AN个体的骨质疏松症,骨质疏松症和喘的发病率较高,但焦虑和抑郁的发病率较低. 更多的AI/AN个人接受医疗补助,生活在非大都市地区.
结论:
- 患有CF的AI/AN儿童住院率的差异凸显出迫切需要CF健康公平倡议.
- 用包容性方法进行进一步的研究对于了解AI/AN不同人群的健康结果至关重要.
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