基于性别的差异在左捆分支捕获在左捆分支区域步调时左捆分支区域步调.
Ilya Y Shadrin1,2, Sara A Coles1, Claus Graff3
1Department of Medicine, Division of Cardiology, Duke University Hospital, Durham, North Carolina, USA.
Pacing and clinical electrophysiology : PACE
|February 25, 2026
概括
在接受LBB区域节奏 (LBBAP) 的患者中,左束枝 (LBB) 捕获标准的性别差异被确定. 较短的R波峰值时间 (RWPT) 在考虑心脏大小时正常化,这表明可能需要性别特定的标准.
科学领域:
- 电子生理学 电子生理学
- 心脏节拍是因为心脏节拍.
- 电心电图是指心电图.
背景情况:
- 左捆分支区域步调 (LBBAP) 是传统步调的替代方案.
- 对于LBB捕获的既定标准缺乏性别特异性考虑,尽管已知QRS持续时间的性别差异.
研究的目的:
- 为了研究满足左束枝 (LBB) 捕获标准的基于性别的差异,对植入后心电图 (ECG) 进行检测.
- 为了确定当前的LBB捕获标准是否需要在LBB区域节奏中进行性别特定的调整.
主要方法:
- 对222名接受双室LBBAP心脏起器植入 (2020-2023) 的患者 (>18岁) 的回顾性分析.
- 评估基线和手术后第一天 (POD1) 电气失调的心电图.
- 根据EHRA 2023共识算法定义的R波峰值时间 (RWPTs) 所定义的左束分支捕获.
主要成果:
- 女性的基线QRS持续时间比男性更短 (122毫秒对126毫秒,p=0.018).
- 58.0%的男性和70.9%的女性 (p=0.058) 满足了LBB捕获标准.
- 女性表现出较短的V6-RWPTs (~7毫秒较短,p=0.0008);当正常化为较小的心脏大小时,差异得到解决.
结论:
- 有LBB捕获的雌性表现出较短的V6-RWPT,但这种差异取决于大小.
- 目前的LBB捕获标准可能不适用于所有性别.
- 需要进一步的研究来确定LBB捕获评估的性别特异性标准.
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