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Updated: Feb 28, 2026

The Forced Swim Test as a Model of Depressive-like Behavior
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在基因与环境相互作用研究中,多基因抑郁症风险评分的预测价值:系统性审查

Sabrina Illius1,2, Julian Eder3, Susanne Vogel4,5

  • 1Department of Psychology, Faculty of Human Sciences, Medical School Hamburg, Am Kaiserkai 1, 20457, Hamburg, Germany. sabrina.illius@medicalschool-hamburg.de.

Translational psychiatry
|February 25, 2026
PubMed
概括

抑郁症的多基因风险评分 (PRSD) 与环境因素相互作用,但基因环境相互作用 (GxE) 对抑郁症的影响是异质的. 大型研究显示了显著的PRSDxE相互作用,特别是最近的暴露,以及基因环境相关性.

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Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
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