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Updated: Feb 28, 2026

Precise Phage Mutagenesis with NgTET-Assisted CRISPR-Cas Systems
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一个膜结合的核酶在基因组注射过程中直接切割菌体DNA

Daniel S Saxton1, Peter C DeWeirdt1,2, Christopher R Doering1

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.

Nature
|February 25, 2026
PubMed
概括

SNIPE是一种新的细菌防御系统,在注射过程中向和分裂菌体DNA,作用于细胞膜. 这一发现揭示了细菌区分病毒DNA与自身的新机制.

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