在慢性压力诱导的抑郁相关结果中,CPT1C的双重调控作用

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Updated: Feb 28, 2026

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice
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A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice

Published on: May 15, 2019

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Dan Tian1, Zhi-Xuan Xia2, Si-Ying Wang1

  • 1Department of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.

Molecular psychiatry
|February 25, 2026
PubMed
概括

卡尼丁棕甲基转移酶1C (CPT1C) 功能障碍通过改变α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid受体 (AMPAR) 功能,导致类似抑郁症的行为. CPT1C可能是主要抑郁症 (MDD) 的治疗点.

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