"爱你的大脑"的统计分析计划:一项多臂随机对照试验,用于预防中风的数字平台
M F Kilkenny1,2, S L Gall3, D A Cadilhac4,5
1Stroke and Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia. Monique.Kilkenny@monash.edu.
Trials
|February 26, 2026
概括
这项研究评估了"爱你的大脑"用于预防中风的数字平台. 它的目的是增加医疗访问心血管风险管理和通过在线课程和短信改善健康行为.
科学领域:
- 数字健康数字健康
- 心血管健康 心血管健康
- 预防中风 预防中风
背景情况:
- 脑卒中影响四分之一的人,但是可以预防的.
- 数字健康工具为中风预防干预提供了一个有希望的途径.
- "爱你的大脑"平台旨在通过数字教育减少中风的发生率.
研究的目的:
- 开发和评估用于预防中风的数字平台.
- 增加参与者访问医疗从业人员进行心血管风险因素管理.
- 改善中风知识,药物坚持和健康行为.
主要方法:
- 一个为期三年的多臂随机对照试验,将一个常见的对照臂与两个干预臂进行比较 (在线课程,短信).
- 样本大小为894名参与者,随机分类1:1:1,按年龄和性别分层.
- 主要结果使用逻辑-二项式回归分析;二次结果使用一般化混合效应回归模型.
主要成果:
- 介绍了统计分析计划,概述了评估数字平台有效性的方法.
- 该研究有能力检测到对主要结果的30%的相对干预效应.
- 治疗意向分析将用于主要结果.
结论:
- 这种统计分析计划确保了对试验结果的透明报告.
- "爱你的大脑"将提供关于预防中风的数字健康教育的新证据.
- 这项研究将有助于理解心血管健康的有效数字干预措施.
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