在预期的干预试验中,在患有尿路疾病的狗和猫身上处方抗菌剂
Amy W Hii1,2, James R Gilkerson1,2, Kirsten E Bailey1,2
1Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Science, University of Melbourne, Parkville, Victoria, Australia.
Journal of veterinary internal medicine
|February 26, 2026
概括
在物中免除尿路疾病的培养和敏感性 (C&S) 测试,减少了抗菌素的处方. 这种干预措施还导致治疗时间缩短,改善了兽医中负责任的抗生素使用.
科学领域:
- 兽医微生物学 兽医微生物学
- 临床药理学 临床药理学
- 抗微生物药物管理委员会
背景情况:
- 对于进行培养和敏感性 (C&S) 测试的兽医来说,成本是很大的障碍.
- 尿路疾病在小动物中很常见,需要明智地使用抗菌药物.
研究的目的:
- 评估免费C&S测试和决定支持工具对兽医抗菌素处方行为对尿路疾病的影响.
- 评估实证抗微生物药物处方频率和治疗持续时间的变化.
主要方法:
- 一项涉及澳大利亚21家兽医诊所的前性队列研究.
- 干预组诊所获得了免费的尿液C&S测试和决策支持工具.
- 对照组的诊所遵循标准实践;分析了两组的临床病史.
主要成果:
- 与对照组相比,干预组显示实证抗菌素处方的可能性降低 (P=.04).
- 干预组中的猫比对照组中的猫 (48%,P=.03) 接受的 cefovecin (22%) 较少.
- 在干预组中,抗菌药物治疗的持续时间明显较短 (P≤.001).
结论:
- 消除微生物诊断测试的成本障碍对抗微生物药物处方产生了积极的影响.
- 提供决策支持工具,以及免费的C&S测试,导致减少了抗菌素处方频率和更短的治疗持续时间.
- 这些发现支持整合可访问的诊断和决策支持,以加强兽医实践中的抗菌药物管理.
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