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对比商业和开放的初始样本转移技术对临床结果和机构成本的影响

Erin H Yang¹, Corina Lopez², Sabra L Shay³

¹Massachusetts General Hospital, USA.

Infection control and hospital epidemiology

|February 26, 2026

概括

从商业ISDT转向开放的初始样本转移技术 (ISDT) 并没有影响污染率或住院等临床结果. 然而,这一变化大大降低了实验室成本.

科学领域:

传染性疾病传染性疾病
临床微生物学临床微生物学
医疗保健经济学医疗保健经济学

背景情况:

商业与开放初始样本转移技术 (ISDT) 的临床疗效和成本效益的比较尚未得到充分证实.
最初的样本转移技术对于获得未受污染的培养至关重要,这会影响患者管理和医疗保健成本.

研究的目的:

为了比较与商业ISDT相关的临床结果和实验室成本,与开放ISDT相比.
评估转换ISDT方法对血液培养污染,停留时间和抗生素利用的影响.

主要方法:

进行了一项多中心研究,比较商业和开放的ISDT.
收集和分析了血液培养污染率,住院时间和抗生素治疗日数的数据.

主要成果:

从商业ISDT切换到开放ISDT并没有显著改变血培污染率.
在两种ISDT方法之间,没有观察到停留时间或抗生素治疗日的显著差异.
通过采用开放的ISDT,实现了与实验室相关成本的显著降低.

结论:

过渡到开放的ISDT提供了一个节省成本的替代方案,而不会影响关键的临床结果,如污染率或患者治疗持续时间.
医疗机构可以考虑实施开放的ISDT,以优化资源配置,同时保持可比的临床结果.

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