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Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
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针对免疫无塑性贫血的自主调节性T细胞的I期试验

Nazia Matto1, Shreyans Gandhi2, Marta Rzepkowska1

  • 1Department of Haematology Medicine, School of Cancer and Pharmaceutical Sciences, SGDP Centre, Denmark Hill, Kings College London, London.

Haematologica
|February 26, 2026
PubMed
概括

调节性T细胞 (Tregs) 疗法对于无形性贫血 (AA) 患者来说是安全的和可扩展的. 这种方法可能有助于恢复免疫平衡,并诱导那些对标准治疗无反应的人的临床反应.

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.