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Updated: Feb 28, 2026

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos
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埃尔拉纳塔马布用于治疗多发性骨髓瘤中枢神经干预不耐其他干预的治疗

Kelley Julian1, Briana Peterson1, Ghulam Rehman Mohyuddin1

  • 1Division of Hematology Huntsman Cancer Institute University of Utah Salt Lake City Utah USA.

EJHaem
|February 26, 2026
PubMed
概括

这项案例研究表明,用elranatamab (双特异性抗体) 和CAR-T细胞进行序列治疗可以有效地治疗中枢神经系统 (CNS) 多发性髓瘤,为预后不佳的患者提供希望.

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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