根ZX3的安全性和有效性用于症状不可逆转的血栓炎:单中心,开放标签,单臂临床试验的协议
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Updated: Jun 16, 2026

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Inducing Apical Periodontitis in Mice
Published on: August 6, 2019
13.1K
Takashi Matsuura1, Asuka Aka1, Hidetaka Ishizaki1
1Department of Periodontology and Endodontology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JPN.
Cureus
|February 26, 2026
概括
根ZX3的高频电流 (HFC) 提供了对症状不可逆转的脉炎 (SIP) 快速缓解疼痛. 这项研究评估了其在治疗牙痛方面的安全性和有效性,并有可能简化紧急内牙科工作流程.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 牙科材料科学 牙科材料科学
背景情况:
- 根ZX3,一个2021年牙科发电机,使用高频电流 (HFC) 快速凝结肉组织.
- 对HFC在治疗症状性不可逆转性脉炎 (SIP) 的证据有限.
- 由于非计划性质和治疗时间,SIP紧急情况会破坏临床工作流程.
研究的目的:
- 评估Root ZX3治疗SIP的安全性和临床有效性.
- 评估自发疼痛的立即缓解 (主要终点).
- 确定HFC应用后不良事件的发生率.
主要方法:
- 单中心,单臂试验涉及10个永久牙与SIP.
- 在准备接入腔之后,使用Root ZX3尖端电极进行HFC应用.
- 在术后第0天进行临时恢复安置和疼痛评估.
主要成果:
- 主要终点:在术后的第0天,自发疼痛的消失.
- 二级终点:不良事件的发生率.
- 数据将告知HFC对急性脉疼痛的有效性.
结论:
- 这项试验为SIP管理提供了Root ZX3的首次系统评估.
- HFC应用旨在有效和安全地简化紧急内牙科工作流程.
- 结果可能会确定Root ZX3作为一种有价值,时间有效的急性脉疼痛缓解的选择.
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