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托芬代谢重编程可能有助于SARS-CoV-2感染小鼠和人类的原血栓环境

Saravanan Subramaniam1,2,3, Marc Arthur Napoleon3, Saran Lotfollahzadeh3

  • 1Department of Pharmacology and Toxicology, School of Pharmacy, Massachusetts College of Pharmacy and Health Sciences, Boston, MA.

Blood vessels, thrombosis & hemostasis
|February 26, 2026
PubMed
概括

严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 感染增加了tryptophan代谢物kynurenine. 这种代谢物激活基碳化合物受体 (AHR) 和组织因子 (TF) 途径,促进COVID-19中的血栓形成.

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