在老年人中,身体活动水平,久坐时间和轻度认知障碍之间的关联
Wei Chen1, Lei Zhang1, Palida Abulizi1
1Department of Geriatrics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Frontiers in public health
|February 26, 2026
概括
身体活动和久坐时间对老年人轻度认知障碍 (MCI) 风险产生影响. 理想的每周体力活动水平 (PAL) 和有限的静坐时间可能会降低MCI发病率.
科学领域:
- 老年学是指老年学的学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 轻度认知障碍 (MCI) 在老年人群中越来越令人担忧.
- 身体活动水平 (PAL) 和久坐行为是影响MCI风险的潜在可修改因素.
- 现有研究表明存在关联,但确切的剂量反应关系需要进一步阐明.
研究的目的:
- 研究老年人身体活动水平 (PAL),久坐时间和轻度认知障碍 (MCI) 之间的关联.
- 探索PAL,久坐时间和MCI风险之间的剂量反应关系.
- 确定身体活动和久坐时间的最佳范围,以减少MCI风险.
主要方法:
- 使用集群采样对1465名老年人的横截面调查.
- 通过蒙特利尔认知评估 (MoCA) 评估的认知功能.
- 使用国际体育活动问卷-简单表格 (IPAQ-SF) 评估体育活动;静坐时间自我报告.
- 使用后勤回归和限制立方线 (RCS) 分析来确定关联和剂量反应关系.
主要成果:
- 较高的PAL四分位数与降低的MCI风险显著相关 (例如,第四个四分位数的OR=0.345).
- 久坐时间的第二四分位数与较低的MCI风险 (OR=0.561) 有关.
- RCS分析显示,MCI风险最低,约为1,485个MET-min/week. PAL,风险增加超过4000MET-min/week. 最佳的静坐时间是每天150分钟,风险在每天200分钟后增加.
结论:
- 身体活动和久坐行为都与老年人中MCI发病率有显著的关联.
- 保持每周的PAL在1,485和4,000MET-min/wk之间. 与降低MCI风险有关.
- 将每日静坐时间限制在200分钟以下可能对老年人的认知健康有益.
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