扩散性脂纤维素瘤与手骨参与:扩大临床谱:一个病例报告和文献综述
Povilas Jurgutavičius1, Mindaugas Minderis2, Mykolas Udrys3
1Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
JPRAS open
|February 26, 2026
概括
本案例研究详细介绍了一名患有上肢扩散性脂纤维素瘤 (LF) 的成年女性,这是一种罕见的瘤. 手术重建显著改善了手的功能,为管理这种不常见的疾病提供了洞察力.
科学领域:
- 在瘤学瘤学.
- 整形外科手术 整形外科手术
- 病理学 病理学 病理学
背景情况:
- 脂纤维素瘤 (LF) 是一种罕见的良性纤维细胞-脂肪细胞瘤.
- 世卫组织将肺炎分类为中间 (局部具有攻击性) 软组织瘤.
- 由于LF的罕见性,诊断标准和治疗指南定义不完善.
研究的目的:
- 在成年时呈现出一种异常罕见的扩散性上肢脂纤维素瘤病例,骨参与.
- 为提供关于脂纤维素瘤病的综合文献综述.
- 提供对脂纤维素瘤病的诊断和重建方法的见解.
主要方法:
- 一个48岁的妇女的病例介绍,她一生都患有软组织质量和手部形.
- 图像 (放射学,MRI) 和组织学检查用于诊断.
- 两阶段的手术重建:瘤切除和指整骨术.
主要成果:
- 确诊的诊断是脂纤维素瘤症,与远距离半径,手腕和指的广泛骨干干涉.
- 手术重建导致了手部功能的大幅恢复.
- 在手臂,肩膀和手的残疾 (DASH) 评分中报告了15.9分的改善.
结论:
- 在脂纤维素瘤症中,骨的参与非常罕见.
- 这一案例凸显了在成人软组织群体中考虑脂肪纤维素瘤的重要性,这对骨有影响.
- 提出的重建方法为管理类似的复杂案例提供了一个潜在的策略.
相关概念视频
Bone Remodeling
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bones of the Upper Limb: Radius
The radius is longer of the two bones that make up the human antebrachium or forearm. At the proximal end, the radius articulates with the capitulum of the humerus and the radial notch of the ulna to form the elbow joint. At the distal end, the radius articulates with the ulna via the ulnar notch, forming the distal radioulnar joint. Distally, the radius also attaches to the carpal wrist bones (scaphoid and lunate) to form the radiocarpal joint.
The radius has a nail-shaped head, and a short...
The radius has a nail-shaped head, and a short...
