使用科罗特科夫声音的特征来评估动脉硬度
Shuqi Ren1, Wei Zhao2,3, Changcheng Yi1
1Key Laboratory of Biomechanics and Mechanobiology (Ministry of Education), Key Laboratory of Innovation and Transformation of Advanced Medical Devices (Ministry of Industry and Information Technology), National Medical Innovation Platform for Industry-Education Integration in Advanced Medical Devices (Interdiscipline of Medicine and Engineering), School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
通过机器学习,可以从Korotkoff声音中提取动脉硬信息,显示出血管衰老评估的潜力. 需要进一步验证临床风险分层超越年龄和血压.
科学领域:
- 生物医学工程 生物医学工程
- 心血管研究研究心血管研究
- 人工智能在医学中的应用
背景情况:
- 动脉硬是血管衰老的关键标志物,并预测心血管事件.
- 对动脉硬性的常规脉冲波速度 (PWV) 评估并不广泛使用.
- 本研究探讨使用科罗特科夫声音进行动脉硬度评估.
研究的目的:
- 为了研究从科罗特科夫声音中提取动脉刚性信息的可行性.
- 应用特征分析和机器学习来分类动脉硬.
- 评估非侵入性血管衰老评估的潜力.
主要方法:
- 收集了来自年轻和年长参与者的科罗特科夫声音.
- 包括一个医院队列,测量了手腕脚PWV (baPWV).
- 提取了时间和频率域特征,并应用了传统和深度学习模型.
主要成果:
- 年龄组之间的提取特征 (质量中心,斜率,峰值频率) 的显著差异.
- 深度学习模型在与年龄相关的群体中实现了高分类准确率 (高达93.7%).
- 在基于baPWV的分类中,表现适度,科罗特科夫声音特征与baPWV之间存在温和的关联.
结论:
- 科罗特科夫声音包含有关血管衰老和动脉硬性的可测量信息.
- 机器学习可以有效地利用这些信号进行群体歧视.
- 为了进行临床风险分层,还需要使用标准化PWV测量进行进一步的大规模研究.
相关概念视频
Korotkoff Sounds
During blood pressure assessment, inflating the cuff 30 millimeters of mercury above the patient's systolic blood pressure...
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Assessment of blood pressure in brachial artery(two-step method)
Assessing Blood pressure using a doppler ultrasound
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Measurement of Blood Pressure
Assessment of the Cardiovascular System IV: Auscultation
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.


