控制营养状况得分作为预测晚期心力衰竭患者心室节律失常的指标
Yuma Ono1, Hidekazu Kondo1, Taisuke Harada2
1Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama, Yufu City, Oita 879-5593, Japan.
ESC heart failure
|February 26, 2026
概括
通过控制营养状况 (CONUT) 评分识别的营养不良独立预测接受心脏再同步治疗 (CRT) 的晚期心力衰竭患者的腹腔失常和死亡率. 营养评估有助于风险分层.
科学领域:
- 心脏病学 心脏病学
- 营养科学 营养科学
- 老年病的医生 老年病的医生
背景情况:
- 心力衰竭 (HF) 患者中普遍存在营养不良,可能会影响预后.
- 在HF患者中,营养不良和心律失常结局之间的关联需要进一步调查.
研究的目的:
- 评估营养不良是否使用控制营养状况 (CONUT) 评分和老年营养风险指数 (GNRI) 预测心室节律失常和全因死亡率.
- 评估营养不良对接受心脏再同步治疗 (CRT) 的晚期HF患者的影响.
主要方法:
- 对167名接受CRT的晚期HF患者进行了回顾性队列研究.
- 在CRT之前,通过CONUT得分和GNRI评估营养状况.
- 主要终点:心室节律失常和所有原因死亡率的组合;中位数随访:1536天.
主要成果:
- 在15.6%的患者中存在CONUT定义的营养不良 (得分≥5),在22.2%的患者中存在GNRI定义的营养不良 (得分<92).
- 根据CONUT定义的营养不良显著预测了主要结果 (日志排名P = .0003) 和心室节律失常 (P = .01).
- CONUT评分独立预测了主要结果 (aHR:2.33),并改善了风险歧视 (C指数:0.695至0.713).
结论:
- 营养不良,特别是根据CONUT评分定义的营养不良,是CRT接受者不良结果的重要独立预测因素.
- 使用CONUT评分进行营养状况评估,可以提高接受CRT的高级HF患者的风险分层.
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