两种染料标记方法的比较,用于在手术前定位由电磁导航支气管镜指导的肺结节
Hao Yang1,2, Kong-Jia Luo1,2, Ying Liang2,3
1Department of Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
Thoracic cancer
|February 26, 2026
概括
用电磁导航支气管镜 (ENB) 引导的染料定位用于肺结节是有效的. 印ocyanine绿色 (ICG) 通过减少程序时间,比甲基蓝 (MB) 提供了潜在的操作效率优势.
科学领域:
- 肺部病理学 肺部病理学
- 胸部外科手术 胸部外科手术
- 医疗成像医学成像
背景情况:
- 由于检测率的增加,肺结节的精确手术前定位至关重要.
- 电磁导航支气管镜 (ENB) 引导的染料标记是一种有效的定位方法.
- 对于ENB引导局部化的最佳染料仍然不清楚,需要进行比较研究.
研究的目的:
- 为了比较甲蓝 (MB) 和绿 (ICG) 的功效和安全性,用于ENB引导的肺结节定位.
- 评估不同染料对手术效率和患者治疗结果的影响.
主要方法:
- 在2015年至2021年期间,对101名接受ENB引导染色本地化 (MB或ICG) 的患者进行了比较研究.
- 主要结果:本地化成功率和与ENB相关的并发症.
- 二级结局:手术时间 (目标时间),冷截面和石结果的一致性,5年整体存活率 (OS) 和无病存活率 (DFS).
主要成果:
- 在所有MB和ICG患者中,成功地实现了局部化,没有严重的并发症.
- 与甲基烯蓝 (MB) 相比,印ocyanine绿 (ICG) 的使用与显著缩短的操作目标时间有关.
- 在MB和ICG组之间,手术内冷截面一致率和5年DFS/OS率是可比的.
结论:
- 以ENB为指导的染料定位是一种安全而准确的技术,用于微创性肺结节切除.
- MB和ICG都是ENB局部化的有效染料.
- 由于运营时间缩短,ICG在运营效率方面显示出潜在的优势.
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