在血液透析患者中抑郁,焦虑和压力症状的长度变化
Adriana-Luciana Luca1, Felicia Militaru2, Mădălina Iuliana Mușat3,4
1U.M.F. Doctoral School Craiova, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Clinics and practice
|February 26, 2026
概括
在血液透析患者中,抑郁和焦虑症状在六个月内显著恶化,这表明精神健康持续下降. 这突显了为透析的慢性病患者提供综合精神健康计划的迫切需要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 具有不可逆转的功能丧失的特点.
- 血液透析 (HD) 患者表现出明显的精神症状,尽管管理方面取得了进展,但精神健康状况持续不佳.
- 该研究的重点是罗马尼亚的背景,HD患者数量不断增加.
研究的目的:
- 调查血液透析患者中抑郁症,焦虑症和压力症状严重性的时间趋势.
- 检查这些心理症状与临床变量之间的相关性,包括透析充分性 (spKt/V).
主要方法:
- 173名血液透析患者的队列接受了全面的精神病学评估.
- 使用的标准化仪器包括社会经济尺度 (SES-3),迷你精神状态检查 (MMSE) 和抑郁,焦虑和压力尺度21R (DASS-21R).
- 收集了临床数据,包括透析性能 (spKt/V) 和查尔森并发症指数 (CCI).
主要成果:
- 在六个月内,抑郁症 (p < 0.0001) 和焦虑症 (p < 0.0001) 症状的严重程度显著增加.
- 压力症状保持稳定 (p = 0.0661),尽管透析足够性的改善 (spKt/V).
- 抑郁症得分与焦虑有中度的相关性,与压力和spKt/V.有微弱的相关性. 焦虑与压力相对应的程度中等,焦虑/压力和spKt/V之间的相关性可以忽略不计.
结论:
- 这项研究证实了血液透析患者精神健康症状的恶化时间趋势和持续性.
- 临床变量对心理结果具有适度的预测价值.
- 迫切需要综合心理健康查,干预计划和针对HD患者量身定制的多学科团队.
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