基于AuNPs的简单和可视色度测试传感器,用于快速检测环境样本中的硫甲
Luwei Chai1, Yarong Wang1, Shuang Jiang1
1Key Laboratory of Conservation and Utilization of Freshwater Fishes, Animal Biology Key Laboratory of Chongqing Education Commission of China, College of Life Sciences, Chongqing Normal University, Chongqing 401331, China.
Biosensors
|February 26, 2026
概括
这项研究开发了一种快速的视觉胃口传感器,用于检测环境样本中的硫甲 (SMZ) 残留物. 该传感器具有高灵敏度和精度,对于监测畜牧业产生的潜在风险至关重要.
科学领域:
- 环境科学 环境科学
- 分析化学 分析化学
- 生物技术是生物技术.
背景情况:
- 硫甲 (SMZ) 是一种常见的兽医抗生素,其在水和土壤中的残留物构成生态和人类健康风险.
- 在环境矩阵中有效监测SMZ对于风险评估和管理至关重要.
研究的目的:
- 开发一种新的,快速的,可视化的适应传感器,用于在环境样本中检测SMZ.
- 通过分子动力学模拟和现实世界样本分析来验证适应传感器的性能.
主要方法:
- 基于金纳米粒子 (AuNP) 的色度感应传感器的构建,采用SMZ1S吸收器.
- 通过线性范围,检测极限和选择性研究,优化传感器条件和性能评估.
- 使用分子动力学模拟和和恢复实验在湖水,自来水和土壤样本中的验证,与HPLC相比.
主要成果:
- 胃感应器显示了广泛的线性范围 (0.050.4μg/mL) 和低检测极限 (0.039μg/mL).
- 分子动力学模拟证实了稳定的aptamer-SMZ结合,支持高传感器选择性.
- 在不同的环境矩阵中,尖峰和恢复测试显示了高准确度 (87.3105.5%) 和精度 (RSD 4.810.6%).
结论:
- 开发的基于AuNP的色度适应传感器是一种简单,有效和快速的工具,用于在环境样本中检测SMZ.
- 传感器的性能相当于HPLC,为现场监控提供了可行的替代方案.
- 这项技术有助于更好地对兽药残留物进行环境监测.
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