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检测禽流感的生物传感器技术:HPAI快速诊断的新前沿

Jacquline Risalvato¹, Alaa H Sewid², Durina Z Dalrymple³

¹Biomedical and Diagnostic Sciences, College of Veterinary Medicine, The University of Tennessee, Knoxville, TN 37996, USA.

|February 26, 2026

概括

高致病性禽流感 (HPAI) 需要快速诊断. 生物传感器技术为及时检测和区分感染者和接种疫苗的动物 (DIVA) 提供了有前途的解决方案,提高了全球家禽健康安全.

科学领域:

兽医病毒学兽医病毒学
生物技术是生物技术.
全球卫生安全全球卫生安全

背景情况:

高致病性禽流感 (HPAI) 对家禽生产,贸易和人类健康构成重大威胁.
目前的诊断方法,如RT-qPCR和ELISA面临的局限性,包括长时间的周转时间,专门的设备需求,和监管限制.
缺乏区分感染者与接种疫苗的动物 (DIVA) 能力阻碍了疫苗接种战略和国际贸易.

研究的目的:

审查目前禽流感诊断的现状.
突出传统诊断方法的局限性.
探索生物传感器技术的潜力,以改善人工智能监测和疾病管理.

主要方法:

审查有关禽流感诊断的现有文献.
评估各种生物传感器平台:电化学,光学,压电和基于核酸的.
分析生物识别策略,性能指标和生物传感器的现场部署能力.

主要成果:

传统的诊断是耗时和资源密集的.
生物传感器平台显示出在现场快速检测禽流感的潜力.
可以开发生物传感器来支持DIVA战略,这对疫苗接种计划和贸易至关重要.

结论:

生物传感器技术为传统的禽流感诊断提供了可行的替代方案.
开发DIVA兼容的生物传感器对于有效的疾病管理和国际贸易至关重要.
生物传感器可以显著提高全球监测,并为控制禽流感的一种健康方法做出贡献.

关键词:

DIVA (区分感染者和接种疫苗的动物)高致病性禽流感 (HPAI) 是一种高度致病性禽流感.一个健康监测健康监测禽流感的诊断方法禽流感的诊断方法生物传感器生物传感器医疗点诊断的诊断方法

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