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间歇性导管使用者与神经障碍的尿路感染的沉默负担:一个范围审查
Floriana D'Ambrosio1, Ciro Pappalardo2, Anna Scardigno2
1Department of Life Sciences, Health and Health Professions, Link Campus University, 00165 Rome, Italy.
Diseases (Basel, Switzerland)
|February 26, 2026
概括
尿路感染 (UTI) 是使用间歇性导管 (IC) 的脊髓损伤 (SCI) 或多发性硬化症 (MS) 的成年人的重大负担. 研究表明,尿路感染的发病率很高,需要更好的管理和更多的研究,特别是对于多发性硬化症患者.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 尿路感染 (UTI) 在患有神经性膀功能障碍的成年人中很常见.
- 间歇性导管 (IC) 是一种管理策略,具有已知的好处,但在实施方面存在挑战.
- 有限的综合数据存在于脊髓损伤 (SCI) 和多发性硬化症 (MS) 患者群体中尿路感染的流行病学负担,使用IC.
研究的目的:
- 综合地绘制和综合有关尿路感染流行病学负担的出版文献.
- 确定患有SCI或MS接受IC的成年人中尿路感染的发生率,患病率和并发症.
- 突出证据差距,并为未来的研究和临床实践提供信息.
主要方法:
- 一个系统的文献审查,遵循PRISMA指南.
- 在PubMed,Scopus和Web of Science中对2014年以来发表的研究进行的搜索.
- 包括30项符合预先定义的分析标准的研究.
主要成果:
- 报告的尿路感染发病率显示出显著的异质性,范围从24%到93.1%.
- 每年,15-17%的患者经历了4-6次尿路感染,高达16.4%的患者因并发症需要住院治疗.
- 发现了大量的证据差距,只有一个研究专注于多发性硬化症 (MS) 患者.
结论:
- 间歇性导管治疗 (IC) 尽管具有临床益处,但仍未得到充分利用和不一致的支持.
- 解决系统性分娩缺口和承认尿路感染是可修改的公共卫生问题至关重要.
- 迫切需要在方法上进行严格的研究,以建立在神经性膀护理中的尿路感染管理的明确最佳实践.
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