巴西珀南布科的COVID-19产妇死亡率相关的因素 (2020-2021):一个病例控制研究
Tacilene Luzia da Silva1, Cristine Vieira do Bonfim2, Ulisses Ramos Montarroyos3
1Postgraduate Program in Tropical Medicine, Center of Medical Sciences, Federal University of Pernambuco, Recife 50670-901, Brazil.
由于压倒性的卫生服务,COVID-19显著增加了孕产妇死亡率. 关键的危险因素包括产后期,更高的平价和低氧和,而发烧似乎是保护性的.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,COVID-19的流行病加剧了孕产妇死亡率.
- 增加与直接病毒影响和紧张医疗保健系统相关的孕产妇死亡率.
- 研究重点关注巴西珀南布科 (2020-2021) 孕产妇死亡的因素.
研究的目的:
- 确定与COVID-19相关的孕产妇死亡相关的社会人口,妊娠和临床因素.
- 分析特定高影响地区的风险和保护因素.
- 在卫生危机期间为减轻孕产妇死亡率的公共卫生战略提供信息.
主要方法:
- 病例对照研究比较37例孕产妇死亡 (病例) 与112名幸存者 (对照).
- 利用条件和Firth的惩罚物流回归用于原始和调整的赔率比率.
- 评估的社会人口统计,妊娠期和临床变量.
主要成果:
- 产后期,平价 (≥1) 和氧和<95%独立地与增加孕产妇死亡风险有关.
- 发烧被认为是预防孕产妇死亡的潜在保护因素.
- 在最终模型中,肥胖和糖尿病并不是独立的预测因素,尽管最初的双变异关联.
结论:
- 孕产妇死亡是一个复杂的,多因素的问题,由流行病加剧.
- 确定的临床和产科漏洞凸显了针对性干预的必要性.
- 研究结果支持改善公共卫生策略和临床方案,以预防未来在紧急情况下发生的孕产妇死亡.
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