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Updated: Jul 31, 2026

Process Development for the Production and Purification of Adeno-Associated Virus AAV2 Vector using Baculovirus-Insect Cell Culture System
10:31

Process Development for the Production and Purification of Adeno-Associated Virus AAV2 Vector using Baculovirus-Insect Cell Culture System

Published on: January 13, 2022

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优化触角流过以实现高产量,可扩展的腺相关病毒下游处理

Sara Cardoso1, Franziska Bollmann1, Alexander Tappe1

  • 1Sartorius Stedim Biotech GmbH, August-Spindler-Straße 11, 37079 Göttingen, Germany.

Membranes
|February 26, 2026
PubMed
概括

这项研究评估了两种接触式流量过 (TFF) 磁带类型,用于腺相关病毒 (AAV) 净化. 电子屏幕录音带提供了更快的处理和更好的杂质去除,而ECO屏幕允许更温和的条件,这两者都证明了AAV下游处理的可扩展性和可重复性.

关键词:
腺相关病毒 (AAV)细胞和基因疗法细胞和基因疗法.下游加工是下游加工.净化 净化 净化 净化接触式流量过器的接流量过器

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