在急性草甘吸入后的双边视神经炎:一个病例报告
Roberta Grasso1, Elena Carapelle1, Maria Eva Terracciano1
1Neurology Unit, Department of Neurosciences, Policlinico Riuniti di Foggia, 71100 Foggia, Italy.
Neurology international
|February 26, 2026
概括
急性草甘暴露可能导致双边视神经炎,一种罕见的视力丧失状况. 及时的皮质类固醇治疗可以导致显著的视力恢复.
科学领域:
- 神经科学是一个神经科学.
- 毒理学 毒理学 毒理学
背景情况:
- 双边视神经炎不常见,通常与炎症,脱或毒素有关.
- 草甘暴露与视神经炎之间的关联很少被记录下来.
研究的目的:
- 在急性草甘暴露后报告双边视神经炎的病例.
- 突出农业化学物质暴露与视神经功能障碍之间的潜在联系.
主要方法:
- 一个66岁的男性农业工人的案例研究,急性吸入草甘暴露.
- 评估了临床表现,磁共振成像 (MRI) 发现,脑脊液 (CSF) 分析和视觉唤起潜力 (VEP).
- 治疗涉及高剂量皮质类固醇治疗.
主要成果:
- 在暴露于草甘几小时后,患者经历了快速的双边视力丧失.
- 核磁共振扫描显示了双侧视神经的强度过高,这表明是视神经炎.
- 视觉唤起的潜能显示出延迟的增加;皮质类固醇治疗导致渐进的临床改善和几乎完全的视觉恢复.
结论:
- 这一案例表明,急性草甘暴露与可逆双边视神经炎之间存在潜在的关联.
- 早期诊断和及时的皮质类固醇干预对于严重病例的良好结果至关重要.
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