2023/24年流感疫苗对德国炎性风湿性疾病患者的影响:来自全国,纵向,自我报告研究的见解
Karolina Gente1, Benedikt Ditz2, Eike Bormann3
1Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Vaccines
|February 26, 2026
概括
流感疫苗接种对于患有炎症性类风湿性疾病 (IRD) 的患者来说是安全有效的. 2023/24年疫苗的副作用很小,流感感染率很低,没有严重病例报告.
科学领域:
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
背景情况:
- 患有炎症性类风湿性疾病 (IRD) 的患者面临流感的风险增加.
- 由于害怕疾病恶化,对疫苗的犹在IRD患者中很常见.
研究的目的:
- 评估2023/24年流感疫苗在IRD患者中的安全性和影响.
- 为此群体提供基于证据的流感疫苗接种建议.
主要方法:
- 展望性,纵向性研究评估疫苗接种后自我报告的结果.
- 在线调查问卷在基线,3个月和6个月进行.
- 在2023年10月至12月期间,全国招募IRD患者.
主要成果:
- 2023/24年流感疫苗耐受性良好,95%的人没有经历疾病过程的影响.
- 50%的人报告了注射部位疼痛等轻微的副作用,41%的人没有副作用.
- 只有8.9%的人感染了流感,没有严重或住院病例; 脊椎关节炎患者表现出更高的易感性.
结论:
- 流感疫苗是安全的,并建议符合条件的IRD患者.
- 接种疫苗显著减少了流感发病率和并发症在这个脆弱的群体.
- 医生应在流感季节之前或期间鼓励IRD患者接种流感疫苗.
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