在高率应力回声心脏成像过程中识别个体心脏收缩值
Fabian Spahiu1, Max Hagemann1, Michelle Ottlik1
1COR-HELIX, Institute of Sport Science, Leibniz University Hannover, Hannover, Germany.
Experimental physiology
|February 26, 2026
概括
我们引入个人心脏收缩值 (iCarT) 来测量运动期间的机械心脏极限. 这种新型标志物,独立于标准测量,显示出显著的个体变异性,突出显示了心脏变形分析的价值.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 生物医学工程 生物医学工程
背景情况:
- 压力回声心电图对于在运动期间诊断心脏功能至关重要.
- 了解正常的心脏变形对炼的反应是有限的.
- 需要新的标记物来评估机械心脏限制.
研究的目的:
- 引入个人心脏收缩值 (iCarT) 作为机械心脏限制的新标记.
- 检查iCarT和标准心血管措施之间的关系.
- 调查运动期间心脏变形的可变性.
主要方法:
- 在心肺运动测试期间,高率运动心声学.
- 评估左心室 (LV) 峰值扭曲,纵向应变 (LS) 和顶端周围应变 (ACS).
- 多项式曲线适配以识别变形参数高原,并根据心率百分比 (%HRmax) 定义iCarT.
主要成果:
- 在群体层面,LS首先稳定 (76%HRmax),其次是ACS (82%HRmax) 和LV扭曲 (83%HRmax).
- iCarT发生在89 ±13%HRmax时,具有显著的个人间变异性.
- 在大多数表现为iCarT的参与者中,LV扭曲是平原的最终参数;与像射出分数这样的常规措施没有发现任何关联.
结论:
- iCarT量化了运动期间心脏变形的个体极限.
- 在iCarT中显著的个人间变异性表明个性化评估是必要的.
- 基于变形的值,特别是LV扭曲,提供了超越传统心血管措施的附加值.
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