尼日利亚5岁以下儿童疟疾的负担,挑战和控制
Lenz Nwachinemere Okoro1, Innocent Ayesiga2, Michael Oppong Yeboah3
1Department of Community Medicine, David Umahi Federal University Teaching Hospital, Uburu, Ebonyi State 840001, Nigeria.
Journal of tropical pediatrics
|February 26, 2026
概括
尼日利亚在控制五岁以下儿童疟疾方面面临重大挑战,尽管有可用的干预措施. 解决区域差异和改善干预覆盖率对于减少这种疾病的高负担至关重要.
科学领域:
- 全球健康 全球健康
- 热带医学 热带医学
- 儿童传染病 儿童传染病
背景情况:
- 疟疾是尼日利亚5岁以下儿童的主要疾病和死亡原因.
- 尼日利亚占全球疟疾病例的25%以上,突出了关键的公共卫生问题.
- 持续存在的挑战阻碍了在这个脆弱的年龄组中有效控制疟疾.
研究的目的:
- 审查和综合有关针对尼日利亚五岁以下儿童的疟疾流行病学,干预措施和控制策略的当前文献.
- 确定疟疾控制工作中的关键挑战和差异.
- 为尼日利亚消除疟疾的未来战略提供信息.
主要方法:
- 一篇关于同行评审的文献,国家报告和自2010年以来出版的政策文件的叙事综述.
- 在PubMed,谷歌学者,Scopus和世卫组织,联合国儿童基金会和尼日利亚卫生部的灰色文献中进行的搜索.
- 遵守SANRA的方法严格性指南,重点研究尼日利亚五岁以下儿童疟疾的研究.
主要成果:
- 尼日利亚儿童的疟疾患病率很高,区域差异很大,特别是在北部和农村地区.
- 促成因素包括社会经济地位,气候和干预覆盖范围不足.
- 挑战包括诊断问题,耐药性,以及不一致地使用长效杀虫网 (LLIN) 等预防措施.
结论:
- 尽管取得了进展和有效的干预措施 (LLINs,间歇性预防疗法,室内残留喷雾),但覆盖和实施仍然存在重大差距.
- 像诊断和疫苗这样的创新工具看起来很有前途,但未得到充分利用.
- 一个协调的,多部门的方法,加强卫生系统和政策改革对于有效控制尼日利亚儿童疟疾至关重要.
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