对于PrEP选择的偏好:美国性少数群体男性之间的离散选择实验的试点研究
Gabriel Robles1, Addam Reynolds2, Uri Amir-Koren3
1Suzanne Dworak-Peck School of Social Work, University of Southern California, Los Angeles, California.
概括
性少数群体的男性更喜欢按需PrEP (暴露前预防),而不是每日或注射方案. 尽量减少副作用和提高同行意识是改善PrEP在这个人群中吸收的关键.
科学领域:
- 公共卫生 公共卫生
- 预防艾滋病毒 预防艾滋病毒
- 性健康 性的健康
背景情况:
- 艾滋病毒不成比例地影响性少数群体 (SMM) 的男性.
- 在这个关键人群中,暴露前预防 (PrEP) 的吸收仍然不够理想.
- 了解SMM偏好对于有效的艾滋病毒预防策略至关重要.
研究的目的:
- 调查艾滋病毒阴性,可接受PrEP的SMM中关于PrEP吸收的偏好和担忧.
- 确定影响PrEP可接受性的关键属性.
主要方法:
- 一个离散选择实验 (DCE) 用于271名艾滋病毒阴性,可接受PrEP的SMM.
- 参与者评估了假设的PrEP个人资料,考虑了管理,副作用,提供者的语言和同行使用.
- 统计分析发现了重要的偏好驱动因素.
主要成果:
- 按需PrEP方案明显优于每日或长效注射配方.
- 不良副作用,特别是头痛和恶心,对PrEP的可接受性有很大的影响.
- 同龄人对PrEP使用的认识与参与者自己使用PrEP的可能性正相关.
- 提供者语言对应性并没有成为优先选择的重要因素.
结论:
- 灵活的PrEP管理选项,特别是按需,对于提高SMM的接受度至关重要.
- 减轻潜在的副作用对于成功实施PrEP至关重要.
- 利用社交网络和同龄人的影响可以增强PrEP的吸收.
- 医疗保健提供和信息应根据SMM的偏好进行定制,以改善艾滋病毒预防结果.
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