一项模拟研究,以评估人口药理动力学模型选择对早产新生儿中万科米辛暴露的贝叶斯预测的影响

Mehdi El Hassani1, Mathieu Blouin1, Van Dong Nguyen1

  • 1Laboratory for Therapeutic Drug Monitoring and Pharmacokinetics, Faculty of Pharmacy, University of Montreal, Quebec, Canada.

概括

选择正确的万科米辛人群药动力学模型对于准确的剂量和实现新生儿治疗目标至关重要. 模型选择显著影响模拟的万科米辛暴露和实现目标的概率.

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