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相关概念视频

Spermatogenesis01:41

Spermatogenesis

124.0K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
124.0K
Spermatogenesis01:22

Spermatogenesis

10.2K
Spermatogenesis is a complex process that involves the development of sperm cells from undifferentiated stem cells in the seminiferous tubules of the testes. The process is essential for the production of mature and functional sperm cells that are capable of fertilizing an egg.
The process of spermatogenesis can be divided into mitosis, meiosis, and spermiogenesis. During mitosis, the spermatogonia or stem cells divide to produce two identical daughter cells, type A and B spermatogonia. Type-A...
10.2K
Testes: Histology01:27

Testes: Histology

3.3K
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
3.3K
Testes: Gross Anatomy01:19

Testes: Gross Anatomy

7.1K
The testes, also known as testicles, are the male gonads. They are housed within the scrotum, a sac-like structure located beneath the penis. The scrotum's primary role is to regulate the temperature of the testes, which is crucial for sperm production.
Each testis is surrounded by the tunica albuginea, a dense connective tissue layer that provides structural support and protection. This layer is covered by an outer serous membrane called the tunica vaginalis, which helps reduce friction...
7.1K
Zygotic Development And Stem Cell Formation01:10

Zygotic Development And Stem Cell Formation

7.0K
The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...
7.0K

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Rapamycin co-exposure fails to reduce cisplatin-induced damage in GC6-spg spermatogonial cell line.

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Machine learning and automation methods for the segmentation, classification and quantification of testicular tissue sections.

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相关实验视频

Updated: Feb 28, 2026

Extra Cellular Matrix-Based and Extra Cellular Matrix-Free Generation of Murine Testicular Organoids
09:18

Extra Cellular Matrix-Based and Extra Cellular Matrix-Free Generation of Murine Testicular Organoids

Published on: October 7, 2020

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如何构建一个丸,细胞逐细胞.

Rod T Mitchell1,2

  • 1Department of Paediatric Endocrinology, Royal Hospital for Children and Young People, Edinburgh, UK.

Science (New York, N.Y.)
|February 26, 2026
PubMed
概括

工程化多能干细胞被开发用于创建功能丸细胞. 这些细胞成功地模仿了天然丸的复杂环境.

科学领域:

  • 干细胞生物学 干细胞生物学
  • 生殖生物学 生殖生物学
  • 发育生物学是发展生物学.

背景情况:

  • 多能干细胞为再生医学提供了潜力.
  • 丸是一个复杂的器官,负责精子的生产和激素的合成.
  • 在体外恢复丸功能仍然是一个重大挑战.

研究的目的:

  • 设计能够分化为体细胞和生殖细胞的多能干细胞.
  • 为了研究目的,开发一个模拟功能丸的模型系统.

主要方法:

  • 使用工程化的多能干细胞.
  • 诱导对丸细胞系的分化.
  • 评估体和生殖细胞的形成.

主要成果:

  • 从工程化多能干细胞成功生成体细胞和生殖细胞.
  • 工程细胞表现出模仿功能丸的特征.

结论:

  • 工程化多能干细胞可以分化为功能丸细胞.
  • 这种方法为研究丸发育和功能提供了一个新的平台.

更多相关视频

Generation of Porcine Testicular Organoids with Testis Specific Architecture using Microwell Culture
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Generation of Porcine Testicular Organoids with Testis Specific Architecture using Microwell Culture

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Isolation of Sertoli Cells and Peritubular Cells from Rat Testes
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Isolation of Sertoli Cells and Peritubular Cells from Rat Testes

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相关实验视频

Last Updated: Feb 28, 2026

Extra Cellular Matrix-Based and Extra Cellular Matrix-Free Generation of Murine Testicular Organoids
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Extra Cellular Matrix-Based and Extra Cellular Matrix-Free Generation of Murine Testicular Organoids

Published on: October 7, 2020

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Generation of Porcine Testicular Organoids with Testis Specific Architecture using Microwell Culture
11:53

Generation of Porcine Testicular Organoids with Testis Specific Architecture using Microwell Culture

Published on: October 3, 2019

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Isolation of Sertoli Cells and Peritubular Cells from Rat Testes
11:11

Isolation of Sertoli Cells and Peritubular Cells from Rat Testes

Published on: February 8, 2016

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