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Updated: Feb 28, 2026

Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease with Fibrosis
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肝硬度通过YAP/TAZ引导肝脏内胆固醇积累 在代谢功能障碍相关的脂肪性肝病中

Na Young Lee1, Myeung Gi Choi1, Ho Jae Ryu1

  • 1College of Pharmacy, Seoul National University, Seoul, Republic of Korea.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 26, 2026
PubMed
概括

与代谢功能障碍相关的脂肪性肝病 (MASLD) 中的肝硬性通过抑制肝 X 受体α (LXRα) 来驱动肝胆固醇的积累. 这种机器敏感通路会损害肝功能,并表明硬度是原因因素.

关键词:
这就是LXRα.马斯尔德 马斯尔德是什么意思雅普/塔兹 (YAP/TAZ) 是一个国家.肝脏硬 肝脏硬 肝脏硬

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