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在护士健康研究II中长期暴露于温度和抑郁症的发生率,这是一项基于美国的前性队列研究
Unnati V Mehta1, Grete E Wilt1, Charlotte J Roscoe2
1Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, United States; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Environment international
|February 26, 2026
概括
较高的年平均温度与患抑郁症的风险增加有关. 这项研究强调了长期暴露于热量的影响精神健康,特别是抑郁症发病率.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 心理健康研究 心理健康研究
背景情况:
- 众所周知,短期的温度波动会影响心理健康住院.
- 长期 (年度) 平均气温与抑郁症发病率之间的关系仍未得到充分研究.
研究的目的:
- 调查年平均气温与抑郁症发病率之间的关联.
- 为了检查长期气候对美国队列精神健康的影响.
主要方法:
- 从护士健康研究II (2001-2019) 中追踪了39,339名参与者,不包括先前存在的抑郁症.
- 将年平均气温数据 (PRISM模型) 与参与者地址联系起来.
- 使用考克斯的比例危险模型来分析抑郁症发病率,对共变量进行调整.
主要成果:
- 年平均温度 (4,9°C) 的四分位数间范围增加与抑郁症发病率增加6%有关 (HR=1.06;95% CI:1.02,1.08).
- 在使用不同结果定义的敏感性分析中,这种关联仍然显著且强大.
结论:
- 持续暴露于更高的年平均温度与抑郁症的风险增加有关.
- 研究结果表明,长期气候状况与慢性心理健康结果之间存在联系.
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