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遗传证据表明,FGF21信号减少了问题性酒精使用和与酒精有关的肝病

Daniel B Rosoff1, Josephin Wagner2, Tyler Perlstein2

  • 1Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA; NIH-Oxford-Cambridge Scholars Program, University of Oxford, UK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.

Journal of hepatology
|February 26, 2026
PubMed
概括

遗传证据表明,纤维细胞生长因子21 (FGF21) 的类似物可以通过行为和代谢变化来减少有问题的酒精使用和与酒精有关的肝病 (ARLD). 这些发现支持FGF21的研究结果.

关键词:
FGF21 模拟模拟的在KLB/FGFR的信号中.马斯德的目标是目标.门德尔的随机化与酒精有关的肝脏疾病.调解 调解 是一种调解方式.整个现象的安全概况.问题性的酒精使用 问题性的酒精使用

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