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Updated: Feb 28, 2026

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益生菌衍生的细胞外囊泡通过肠肝轴减轻胆固醇性肝损伤

Xianjiao Liu1, Yanyan Wang1, Andrea Abreo Medina1

  • 1College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China; Institute of Animal Nutritional Health, Nanjing Agricultural University, Nanjing, Jiangsu, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.

Pharmacological research
|February 26, 2026
PubMed
概括

益生菌 Lactobacillus amylovorus 细胞外囊泡 (LAEVs) 通过调节肠道微生物群 - 胆酸 - ROS 轴来防止肝损伤和纤维化. LAEV恢复了肠道屏障功能,并激活了对肝脏健康至关重要的FXR/FGF-15通路.

关键词:
胆固醇性肝脏疾病是一种肝脏疾病.法尔内索伊德的X受体胆酸胆酸是一种胆酸.细胞外囊泡中的细胞外囊泡.我们的肠道微生物群.

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