适应的力量:弹性和改变期望如何影响安慰剂效应
Sharon Thomas1, Barbara Resnick2, N Jennifer Klinedinst2
1Pain and Translational Symptom Science, University of Maryland School of Nursing, Baltimore, MD, USA.
The journal of pain
|February 26, 2026
概括
疼痛弹性,从疼痛中反弹的能力,预测了更好的治疗结果. 它通过改善患者在积极的治疗经验后更新预期的方式来增强安慰剂效应.
科学领域:
- 心理学 心理学 心理学
- 疼痛管理 疼痛管理
- 神经科学是一个神经科学.
背景情况:
- 治疗期望显著影响疼痛结果和经验.
- 安慰剂干预可以调整期望,并提供疼痛缓解.
- 疼痛性是一种心理特征,与更好的疼痛恢复和安慰剂反应能力有关.
研究的目的:
- 为了研究疼痛抵抗力和疼痛干扰之间的关联.
- 通过强化对疼痛减轻的预期,检查疼痛抵抗力是否预测了安慰剂效应.
- 探索期望更新在性和安慰剂止痛之间关系中的调解作用.
主要方法:
- 152名患有慢性口腔面部疼痛的参与者接受了安慰剂干预,并进行了经典的调节和建议.
- 在调节前和之后评估疼痛减轻期望.
- 管理的自我报告措施包括疼痛性度量,乐观,疼痛灾难化和抑郁症等级.
- 在统计分析中对心理和人口学变量进行控制.
主要成果:
- 疼痛抵抗力与疼痛干扰有负相关性 (p=.037).
- 疼痛抵抗力与强化对止痛的预期正相关 (p=.004),即使在控制其他因素后也是如此.
- 强化期望,而不是基线期望,调解了弹性和安慰剂效应之间的联系 (95% CI = 0.0003至0.0758).
结论:
- 疼痛耐受性与较低的疼痛干扰和增强的安慰剂止痛作用有关.
- 在积极的治疗经验之后,更新预期的能力是连接性与安慰剂效应的关键机制.
- 针对性和预期更新的干预措施可能会改善慢性疼痛治疗的响应能力.
关键词:
慢性或面部疼痛 慢性或面部疼痛调整条件 调整条件更新预期的更新.预期 期望 预期 预期学习 学习 学习 学习 学习疼痛适应能力 疼痛适应能力预测 预测 预测心理特征 心理特征 心理特征对治疗的反应性更多相关视频
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