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Updated: Feb 28, 2026

Polyethyleneimine-coated Iron Oxide Nanoparticles as a Vehicle for the Delivery of Small Interfering RNA to Macrophages In Vitro and In Vivo
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Polyethyleneimine-coated Iron Oxide Nanoparticles as a Vehicle for the Delivery of Small Interfering RNA to Macrophages In Vitro and In Vivo

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多功能pH响应的纳米载体,用于向的阿齐思罗米辛输送和在细菌败血症中免疫调节

Siran Wang1, Lu Yuan2, Chang Gao3

  • 1Translational Medicine Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China; University of Groningen and University Medical Center Groningen, Department of Biomaterials & Biomedical Technology, 9713AV, Groningen, the Netherlands; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Functional Polymer Materials of Ministry of Education, Institute of Polymer Chemistry, College of Chemistry, Nankai University, 300071, Tianjin, China; Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, 325001, Zhejiang, China.

Acta biomaterialia
|February 26, 2026
PubMed
概括

这项研究提出了对pH敏感的细胞,可以将亚齐思罗素输送到细菌生物膜中,从而增强根除. 微粒还与病原体相关的分子模式结合,减少炎症并改善毒症模型中的存活率.

关键词:
急性腹膜炎是一种急性腹膜炎这是一种抗炎药物.它是一种抗菌药物,具有抗菌作用.抗生素耐药性 抗生素耐药性迈塞尔斯 (Micelles) 是一个非常有价值的人.纳米医药是一种纳米医药.

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