在临床上怀疑pterygium的恶性黑色细胞病变
Rozina Ida Hajdu1, Paola Kammrath Betancor1, Othmane Touirssa1
1Eye Center, Medical Center - University of Freiburg, Freiburg, Germany.
The British journal of ophthalmology
|February 26, 2026
概括
恶性黑色细胞病变可以模仿pterygia,其中0.30%的假定pterygium标本显示出像结膜黑色素瘤这样的意想不到的恶性病变. 常规组织病理学对于准确的诊断至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 皮肤病理学 皮肤病理学
- 在瘤学瘤学.
背景情况:
- 菌是常见的结膜生长.
- 恶性黑色细胞病变有时可以模仿pterygia.
- 早期和准确的诊断对于管理眼表面恶性瘤至关重要.
研究的目的:
- 为了确定临床诊断为pterygia的标本中恶性黑色细胞病变的患病率.
- 描述这些病变的临床病理特征.
- 强调组织病理学检查的重要性.
主要方法:
- 对被诊断为pterygia的结膜样本进行了回顾性分析.
- 包括从1999年8月到2024年8月的标本.
- 鉴定出恶性黑色细胞病变的临床和病理特征的审查.
主要成果:
- 在2298个 (0.30%) 标本中,有7个显示出恶性黑色素细胞病变.
- 四个病例是侵袭性结膜黑色素瘤 (0.17%).
- 三个病例是高度的结膜色素细胞内皮层病变 (C-MIL) (0.13%).
- 三种黑色素瘤是美伦性/低黑色素瘤 (75%) 或具有非典型的时间位置 (75%).
结论:
- 恶性黑色细胞病变可以发生在或类似于pterygia.
- 色素呈现使临床诊断复杂化.
- 对所有切除的菌体进行组织病理学评估对于检测意外恶性瘤,如结膜黑色素瘤和C-MIL至关重要.
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