定制制造的22G与商用25G系统的同一会话验证,用于EUS引导门户压力梯度测量
Michael Praktiknjo1, Nancy Farouk1, Zeyu Wang1
1Department of Medicine B, University Hospital Münster, Münster, Germany.
United European gastroenterology journal
|February 26, 2026
概括
一个新的22度内镜超声波系统用于测量门口压力梯度 (EUS-PPG) 显示与现有方法的良好相关性. 这种经过验证的系统提供了一种具有成本效益和可访问的替代方案,用于评估门性高血压.
科学领域:
- 胃肠病学 胃肠病学
- 医疗器械 医疗器械
- 诊断技术 诊断技术的使用
背景情况:
- 以内镜超声导向的门口压力梯度 (EUS-PPG) 测量是肝静脉压力梯度 (HVPG) 评估的新兴替代方案.
- 现有的25度 (25G) EUS-PPG系统与HVPG的相关性很好,但具有包括小口径和专有组件在内的局限性.
- 为了解决这些局限性,开发了一种定制的22-gauge (22G) 常规血管内压力传感器系统.
研究的目的:
- 为了验证定制的22G EUS-PPG系统与商业的25G系统相比.
- 评估两种系统之间的门脉压梯度 (PPG),门脉压 (PVP) 和肝脉压 (HVP) 测量的相关性和可变性.
主要方法:
- 一项前性队列研究,涉及26名患者.
- 同时使用25G商用系统和定制的22G系统进行EUS-PPG测量.
- 主要结果:PPG值的相关性;次要结果:PVP和HVP的相关性和可变性.
主要成果:
- 在两种系统的PPG值之间发现了很好的相关性 (r=0.901,p<0.001).
- 在96.2%的病例中,25G EUS-PPG系统正确识别了临床显著的门性高血压 (PPG ≥10mmHg).
- 在系统之间观察到PVP (r=0.776) 和HVP (r=0.673) 的显著相关性,变化很低.
结论:
- 来自商业25G和定制22GEUS-PPG系统的测量得到了验证,并显示出高度一致.
- 定制的22G系统具有优势,因为它具有压力跟踪质量控制,更广泛的可用性和成本效益.
- 这项研究支持了22G EUS-PPG系统作为评估门高血压的可靠工具的临床实用性.
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