对患有空鼻综合征的患者的集群分析及其与外科手术结果的关系
Chia-Hsin Lu1, Yun-Shien Lee2,3, Pei-Wen Wu1,4,5
1School of Medicine, Chang Gung University, Taoyuan, Taiwan.
The Laryngoscope
|February 26, 2026
概括
患有空鼻综合征 (ENS) 的患者根据症状严重程度被分为四组. 在ENS患者的高心理负担显著增加了重建性手术后持续症状的风险.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 鼻科 鼻科是指鼻科的专家.
- 外科手术的结果
背景情况:
- 空鼻综合症 (ENS) 呈现出多种不同的症状和不可预测的外科手术结果.
- 25项的鼻结局测试 (SNOT-25) 测量鼻症状,但其在分层ENS患者资料中的实用性未得到充分研究.
- 粘膜下Medpor植入是ENS的手术选择,但患者选择和结果预测仍然具有挑战性.
研究的目的:
- 通过等级分类,使用手术前的SNOT-25子域得分来分层空鼻综合征 (ENS) 患者.
- 调查确认的症状集群和在重建性手术后的术后结果之间的关联.
- 为了提高对ENS患者治疗成功的预测.
主要方法:
- 对168名经历了下Medpor植入的ENS患者 (2015-2023) 的回顾性分析.
- 手术前的SNOT-25子域得分被Z标准化,并经过分层聚合集群.
- 使用空鼻综合征6项问卷 (ENS6Q) 评估术后结果,持续症状定义为6个月后ENS6Q分数≥11.
主要成果:
- 在ENS患者中发现了四个不同的症状集群.
- 集群2,以高睡眠和心理负担为特征,表现为持久症状 (0.43) 的最高正预测值 (PPV).
- 集群1具有最高的整体症状负担 (PPV=0.39),而集群4具有最轻微的症状和最低的PPV (0.08).
结论:
- 在ENS患者中,显著的心理负担是术后持续症状的关键预测因素.
- 在全面的手术前症状评估基础上对ENS患者进行分层,可以提高预测结果的准确性.
- 个性化治疗策略由基于症状的聚类来告知,可以优化ENS患者的手术结果.
更多相关视频
08:03Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
313
07:22Surgical Robot-Assisted Transanal Specimen Extraction Radical Sigmoidectomy Without an Auxiliary Abdominal Incision
Published on: June 13, 2025
1.1K
相关概念视频
Epistaxis
657
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
657
Nose and Nasal Cavity
13.4K
The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
13.4K
Olfactory Receptors: Location and Structure
12.3K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
12.3K
Suctioning the Nasopharyngeal Airway
4.1K
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
Equipment Required
4.1K
