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Updated: Feb 28, 2026

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats
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Published on: March 1, 2022

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不调节的Klotho和FGF23信号加剧了与年龄相关的肺高血压中的血管重塑

Paul-Lennard Perret1,2,3,4, Jonathan H Kim1,2,3, Annika Winkler5

  • 1Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117 Berlin, Germany.

Cardiovascular research
|February 27, 2026
PubMed
概括

衰老通过增加FGF23.3加剧肺动脉高血压 (PAH). 针对Klotho/FGF23信号可能为老年PAH患者提供新的治疗策略.

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