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语音唤起的皮质听力潜力作为耳植入物儿童听力成熟的生物标志物
Zeynel Abidin Karatas1, Cengiz Durucu2
1Department of Otorhinolaryngology, Duztepe Yasam Hospital, Gaziantep 27300, Turkey.
Children (Basel, Switzerland)
|February 27, 2026
概括
小儿耳植入物 (CI) 使用者与正常听力同龄人相比,听力皮层成熟的延迟,但随着长时间使用植入物,P1延迟时间会缩短,表明可塑性. 语音唤起的皮质听觉唤起潜能 (CAEPs) 有效地测量了这种发展.
科学领域:
- 神经科学是一个神经科学.
- 听力学 听力学是指听力学.
- 发育儿科 发育儿科
背景情况:
- 听觉皮层成熟对于儿童语音感知发展至关重要.
- 耳植入物 (CIs) 的目的是恢复听力,但听觉系统的发育可能会有所不同.
- 皮质听觉唤起潜能 (CAEP) 提供了听觉处理的客观指标.
研究的目的:
- 评估儿科耳植入物 (CI) 用户的听觉皮层成熟度.
- 为了比较IC使用者的P1延迟与年龄相匹配的正常听力 (NH) 同龄人.
- 检查皮质可塑性P1潜伏,年龄和CI持续时间之间的关系.
主要方法:
- 70名儿童 (40名IC使用者,30名NH对照者) 接受了CAEP记录.
- 语音令牌 (/m/, /g/, /t/) 在自由场设置中呈现.
- 使用t测试和皮尔森相关性 (p <0.05) 分析了P1延迟.
主要成果:
- 与NH同行相比,CI使用者对/m/和/t/刺激的P1延迟时间显著更长.
- 在NH儿童中,P1潜伏与年龄负相关,表明成熟.
- 在CI用户中,更长的植入物使用时间与所有语音令牌的P1延迟时间更短相关.
结论:
- 语音唤起的CAEP是儿童CI使用者的听觉皮层发育的敏感,客观的测量.
- P1延迟反映了时间和听力年龄相关的成熟.
- 在儿科CI护理中,P1延迟作为皮质可塑性和康复进展的生物标志物.
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相关概念视频
Hair Cells
Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
The Cochlea
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.