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在患有先天性CMV感染的患者中听力障碍的随访

Ron Fisher¹, Miriam Geal Dor^2,3, Cahtia Adelman^2,3

¹Department of Otolaryngology-Head and Neck Surgery, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112102, Israel.

Children (Basel, Switzerland)

|February 27, 2026

概括

先天性细胞大脑病毒 (cCMV) 可以导致神经传感器听力损失 (SNHL),这种听力损失在出生时或在儿童时期晚些时候出现. 患有cCMV相关SNHL的儿童表现出动态的,不对称的听力模式,需要长期监测.

科学领域:

儿科儿科儿科
听力学听力学是指听力学.
传染性疾病传染性疾病

背景情况:

先天性细胞大脑病毒 (cCMV) 是儿童感觉神经听力损失 (SNHL) 的主要非遗传原因.
由于cCMV引起的听力损伤可以在出生时表现出来,或在儿童期晚些时候发展,表现出多样化和不断演变的结果.
了解这些听力轨迹对于及时干预和管理至关重要.

研究的目的:

描述诊断为cCMV的儿童的听力轨迹和侧面性模式.
在cCMV感染的背景下,区分先天性和延迟发作的SNHL.
确定影响这一群体听力结果的关键因素.

主要方法:

对儿童进行了回顾性分析,确认了cCMV和纵向听力学随访.
听力损失被归类为先天性SNHL或延迟发作的SNHL.
分析了听力学数据,包括更好和更差的耳朵值,双边参与和纵向变化.

主要成果:

在195名儿童中,59名 (30%) 患有SNHL;34名 (17%) 患有先天性SNHL,25名 (16%) 患有晚发SNHL.
迟发性SNHL出现在最初无症状或出生时有非听觉症状的儿童中.
纵向数据显示,随着时间的推移,36个耳朵的SNHL发展,在延迟发病的病例中保留了更好的耳朵值,而较差的耳朵值在不同组中是相似的.

结论:

患有cCMV相关SNHL的儿童表现出动态和不对称的听力变化,先天性和延迟发作的形式之间存在明显的差异.
风险分层,长期监测方法对于对受cCMV影响的儿童进行个性化监测至关重要.
持续遵守后续监测对于管理这个队列中不断变化的听力损失至关重要.

关键词:

产生的CMV是先天性的.延迟发病的SNHLHL是一种延迟发病的SNHL.后续行动后续行动听力监测听力监测监测渐进性听力损失是一种听力损失.

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Cytomegalovirus Disease

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