相关实验视频
Updated: Feb 28, 2026

10:35
Precision Measurements and Parametric Models of Vertebral Endplates
Published on: September 17, 2019
6.9K
在渐进的腰椎盘退化下对参数有限元素重分配负荷的评估
Oleg Ardatov1,2, Sofia Rita Fernandes3, Artūras Kilikevičius2
1Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania.
Bioengineering (Basel, Switzerland)
|February 27, 2026
概括
有限元分析显示,椎间盘 (IVD) 退化显著改变脊柱力学. 随着磁盘的退化,纤维状环承受着更多的压力,而纤维状核失去了承载能力.
科学领域:
- 生物力学 生物力学
- 生物医学工程 生物医学工程
- 整形外科 整形外科 整形外科
背景情况:
- 椎间盘 (IVD) 退化是腰部疼痛的常见原因之一.
- 了解IVD退化的生物力学后果对于开发有效的治疗方法至关重要.
研究的目的:
- 使用有限元素 (FE) 模型研究与人类腰椎 (L1-L3) 椎间盘退化相关的生物机械变化.
- 在退化过程中量化应力和负载转移机制的再分配.
主要方法:
- 开发了一个CT衍生FE模型的L1-L3腰椎段.
- 通过降低磁盘高度和核脉动体积以及改变组织硬度来模拟退化.
- 应用了位移控制的压力负荷来分析应力分布和反应力.
主要成果:
- 严重的退化导致annulus纤维化应激增加了175%,核纤维化应激减少了70%.
- 在退化的磁盘中,内压力 (IDP) 降低了40-70%.
- 模型预测与尸体和体内数据保持一致.
结论:
- 退化导致显著的负载再分配,增加了纤维环的压力,并减少了细胞核的承载作用.
- 该FE模型提供了关于IVD退化的进展及其生物力学影响的见解.
- 结果可以为临床决策和脊柱植入物和干预措施的设计提供信息.
相关概念视频
Deformation of Member under Multiple Loadings
519
When a rod is made of different materials or has various cross-sections, it must be divided into parts that meet the necessary conditions for determining the deformation. These parts are each characterized by their internal force, cross-sectional area, length, and modulus of elasticity. These parameters are then used to compute the deformation of the entire rod.
In the case of a member with a variable cross-section, the strain is not constant but depends on the position. The deformation of an...
In the case of a member with a variable cross-section, the strain is not constant but depends on the position. The deformation of an...
519
Load along a Single Axis
672
In structural engineering, the analysis of beams subjected to varying loads is a critical aspect of understanding the behavior and performance of these structural elements. A common scenario involves a beam subjected to a combination of different load distributions.
Consider a beam of length L subjected to a varying load, which is a combination of parabolic and trapezoidal load distribution along the x-axis. In this case, it is essential to determine the resultant loads, their locations, and...
Consider a beam of length L subjected to a varying load, which is a combination of parabolic and trapezoidal load distribution along the x-axis. In this case, it is essential to determine the resultant loads, their locations, and...
672
Plastic Deformations of Members with a Single Plane of Symmetry
413
When a structural member undergoes plastic deformation due to bending, it is crucial to understand the position of the neutral axis and the stress distribution. This member, characterized by a single plane of symmetry, exhibits a uniform stress distribution, with negative stress above the neutral axis and positive stress below. Notably, the neutral axis does not align with the centroid of the cross-section. This misalignment is typical in cases where the cross-section is not rectangular or...
413
Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity
648
Deformation occurs in axial and transverse directions when an axial load is applied to a slender bar. This deformation impacts the cubic element within the bar, transforming it into either a rectangular parallelepiped or a rhombus, contingent on its orientation. This transformation process induces shearing strain. Axial loading elicits both shearing and normal strains. Applying an axial load instigates equal normal and shearing stresses on elements oriented at a 45° angle to the load axis.
648
Elastic Curve from the Load Distribution
545
The structural behavior of beams under distributed loads is critical for engineering analysis, which focuses on predicting how beams bend and react under such conditions. Different types of beams (e.g., cantilever, supported, or overhanging) behave differently under distributed load conditions.
For all beams, the analysis of the beam's reaction to distributed loads begins by understanding the relationship between a beam's load and the resulting shear forces and bending moments. Initially, this...
For all beams, the analysis of the beam's reaction to distributed loads begins by understanding the relationship between a beam's load and the resulting shear forces and bending moments. Initially, this...
545
