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Updated: Feb 28, 2026

In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity
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对皮肤状细胞癌的基因组洞察力

Grace S Saglimbeni1, Tyson J Morris1, Beau Hsia1

  • 1School of Medicine, Creighton University, Phoenix, AZ 85012, USA.

Cancers
|February 27, 2026
PubMed
概括

这项研究揭示了皮肤状细胞癌 (cSCC) 中的关键遗传突变,识别了像p53和Notch信号传递等受损的途径. 这些发现提升了对cSCCCC的理解.

关键词:
在AACR项目GENIE中.在NOTCH1中,这就是TP53的特点.生物标志物发现发现癌症基因组学 癌症基因组学副本编号的修改 副本编号的修改皮肤状细胞癌瘤其他非黑色素瘤性皮肤癌身体突变 - 身体突变

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